Application of Deep Learning on Large-Scale Dental Imaging for Automated Diagnosis and Treatment Planning in Orthodontics and General Dentistry

Authors

  • Harlee C. Cruzatt School of Dentistry, San Luis Gonzaga University, Ica and School of Dentistry, Faculty of Medicine, Catholic University Santo Toribio de Mogrovejo, Lambayeque, Peru
  • Mariam Nicole Candelaria Department of Dentistry, Universidad Central del Este, San Pedro de Macorís, Republica Dominicana
  • Noelia Zandra Ramírez Department of Dentistry, Universidad de San Martín de Porres, Lima, Peru
  • Dianet Sierra Gonzalez Universidad de Ciencias Médicas de La Habana, Cuba
  • Melissa Rodriguez Herrera Universidad de Ciencias Médicas de La Habana, Cuba
  • Rayner Lopez Machado Universidad de Ciencias Médicas de La Habana, Cuba
  • Nayara Gonzaga Universidade Católica de Brasília, Distrito Federal, Brazil

DOI:

https://doi.org/10.54536/ajmsi.v5i2.8208

Keywords:

Automated Diagnosis, Deep Learning, Dental Imaging, Explainable AI, General Dentistry, Orthodontics, Treatment Planning

Abstract

Dental imaging plays an important role in automated diagnosis, treatment planning, and clinical decision-making in orthodontics and general dentistry. Early and accurate identification of dental abnormalities from radiographic images can assist dentists in detecting pathological conditions, evaluating anatomical structures, and supporting effective treatment strategies. This study aims to apply deep learning on large-scale dental imaging for automated diagnosis and treatment planning support in orthodontics and general dentistry. For this research, a large dental radiographic image dataset was used, containing training, validation, and testing image samples with multiple dental conditions and anatomical categories. The proposed framework applied deep learning-based feature extraction, K-means pseudo-label clustering, and supervised classification models to classify dental image patterns into four cluster-based diagnostic groups. Model performance was evaluated using accuracy, precision, recall, F1-score, confusion matrix, ROC curve, precision–recall curve, training-validation accuracy and loss curves, and LIME-based explainable artificial intelligence analysis. The results show that the proposed model achieved strong classification performance with an overall accuracy of 99.62% on 1,580 test images. The confusion matrix showed that most predictions were correctly classified across all four clusters, while ROC and precision–recall curves demonstrated excellent discriminative capability. The LIME visualization further indicated that the model focused on clinically meaningful dental and maxillofacial regions during prediction. The findings suggest that deep learning-based dental image analysis can support automated diagnosis, improve diagnostic efficiency, and contribute to preliminary treatment planning in orthodontics and general dentistry.

Downloads

Download data is not yet available.

References

Chen, I. D. S., Yang, C.-M., Chen, M.-J., Chen, M.-C., Weng, R.-M., & Yeh, C.-H. (2023). Deep Learning-Based Recognition of Periodontitis and Dental Caries in Dental X-ray Images. Bioengineering, 10(8), 911. https://doi.org/10.3390/bioengineering10080911

Hwang, J.-J., Jung, Y.-H., Cho, B.-H., & Heo, M.-S. (2019). An overview of deep learning in the field of dentistry. Imaging Science in Dentistry, 49(1), 1. https://doi.org/10.5624/isd.2019.49.1.1

Katsumata, A. (2023). Deep learning and artificial intelligence in dental diagnostic imaging. Japanese Dental Science Review, 59, 329–333. https://doi.org/10.1016/j.jdsr.2023.09.004

Lee, J.-H., Kim, Y.-T., Lee, J.-B., & Jeong, S.-N. (2020). A Performance Comparison between Automated Deep Learning and Dental Professionals in Classification of Dental Implant Systems from Dental Imaging: A Multi-Center Study. Diagnostics, 10(11), 910. https://doi.org/10.3390/diagnostics10110910

Lee, S., Oh, S., Jo, J., Kang, S., Shin, Y., & Park, J. (2021). Deep learning for early dental caries detection in bitewing radiographs. Scientific Reports, 11(1), 16807. https://doi.org/10.1038/s41598-021-96368-7

Sivari, E., Senirkentli, G. B., Bostanci, E., Guzel, M. S., Acici, K., & Asuroglu, T. (2023). Deep Learning in Diagnosis of Dental Anomalies and Diseases: A Systematic Review. Diagnostics, 13(15), 2512. https://doi.org/10.3390/diagnostics13152512

Yang, J., Xie, Y., Liu, L., Xia, B., Cao, Z., & Guo, C. (2018). Automated Dental Image Analysis by Deep Learning on Small Dataset. 2018 IEEE 42nd Annual Computer Software and Applications Conference (COMPSAC), 492–497. https://doi.org/10.1109/COMPSAC.2018.00076

Li, X., Zhao, D., Xie, J., Wen, H., Liu, C., Li, Y., Li, W., & Wang, S. (2023). Deep learning for classifying the stages of periodontitis on dental images: A systematic review and meta-analysis. BMC Oral Health, 23(1), 1017. https://doi.org/10.1186/s12903-023-03751-z

Chaurasia, A., Namachivayam, A., Koca-Ünsal, R. B., & Lee, J.-H. (2024). Deep-learning performance in identifying and classifying dental implant systems from dental imaging: A systematic review and meta-analysis. Journal of Periodontal & Implant Science, 54(1), 3. https://doi.org/10.5051/jpis.2300160008

Cejudo, J. E., Chaurasia, A., Feldberg, B., Krois, J., & Schwendicke, F. (2021). Classification of Dental Radiographs Using Deep Learning. Journal of Clinical Medicine, 10(7), 1496. https://doi.org/10.3390/jcm10071496

Li, W., Liang, Y., Zhang, X., Liu, C., He, L., Miao, L., & Sun, W. (2021). A deep learning approach to automatic gingivitis screening based on classification and localization in RGB photos. Scientific Reports, 11(1), 16831. https://doi.org/10.1038/s41598-021-96091-3

Yang, C., Bai, L., & Su, J. (2026). AI-Enabled Dental Care. Regenerative Medicine and Dentistry, 3(1), 3. https://doi.org/10.53941/rmd.2026.100003

Krois, J., Garcia Cantu, A., Chaurasia, A., Patil, R., Chaudhari, P. K., Gaudin, R., Gehrung, S., & Schwendicke, F. (2021). Generalizability of deep learning models for dental image analysis. Scientific Reports, 11(1), 6102. https://doi.org/10.1038/s41598-021-85454-5

Esmaeilyfard, R., Bonyadifard, H., & Paknahad, M. (2024). Dental Caries Detection and Classification in CBCT Images Using Deep Learning. International Dental Journal, 74(2), 328–334. https://doi.org/10.1016/j.identj.2023.10.003

Manjunatha, V. A., Parisarla, H., & Parasher, S. (2024). A systematic review on recent advancements in 3D surface imaging and artificial intelligence for enhanced dental research and clinical practice. IP International Journal of Maxillofacial Imaging, 10(4), 132–139. https://doi.org/10.18231/j.ijmi.2024.029

Park, W., Schwendicke, F., Krois, J., Huh, J.-K., & Lee, J.-H. (2023). Identification of Dental Implant Systems Using a Large-Scale Multicenter Data Set. Journal of Dental Research, 102(7), 727–733. https://doi.org/10.1177/00220345231160750

Lee, H. J., How, R. A. W. M., Gan, K. B., Ashari, A., Syed Mohamed, A. M. F., & Megat Abdul Wahab, R. (2026). Development of Leading Enhancement Assistive Planning: A three-dimensional malocclusion classification system for orthodontic treatment with clear aligners. Korean Journal of Orthodontics. https://doi.org/10.4041/kjod25.214

Hao, J., Liao, W., Zhang, Y. L., Peng, J., Zhao, Z., Chen, Z., Zhou, B. W., Feng, Y., Fang, B., Liu, Z. Z., & Zhao, Z. H. (2022). Toward Clinically Applicable 3-Dimensional Tooth Segmentation via Deep Learning. Journal of Dental Research, 101(3), 304–311. https://doi.org/10.1177/00220345211040459

Ali, M., Irfan, M., Ali, T., Wei, C. R., & Akilimali, A. (2025). Artificial intelligence in dental radiology: A narrative review. Annals of Medicine & Surgery, 87(4), 2212–2217. https://doi.org/10.1097/MS9.0000000000003127

Kaushik, R., & Rapaka, R. (2025). AI-driven evolution in teledentistry: A comprehensive overview of technology and clinical applications. Dentistry Review, 5(2), 100154. https://doi.org/10.1016/j.dentre.2025.100154

Makrygiannakis, M. A. (2026). Assessment of AI software’s diagnostic accuracy in identifying impacted teeth in panoramic radiographs. European Journal of Orthodontics, 47(5), Article cjaf085. https://doi.org/10.1093/ejo/cjaf085

Sum, H. Y. O. (2025). A Chronological Narrative Review of AI Evolution in Dentistry. Pakistan Journal of Life and Social Sciences (PJLSS), 23(1). https://doi.org/10.57239/PJLSS-2025-23.1.00597

Ba-Zar, Dr. O. A., Mehtiyeva, Dr. N., & Almizban, Dr. N. S. (2025). The Role of AI in Modern Aesthetic Dentistry. Saudi Journal of Oral and Dental Research, 10(09), 343–351. https://doi.org/10.36348/sjodr.2025.v10i09.002

Dot, G., Chaurasia, A., Dubois, G., Savoldelli, C., Haghighat, S., Azimian, S., Taramsari, A. R., Sivaramakrishnan, G., Issa, J., Dubey, A., Schouman, T., & Gajny, L. (2024). DentalSegmentator: Robust open source deep learning-based CT and CBCT image segmentation. Journal of Dentistry, 147, 105130. https://doi.org/10.1016/j.jdent.2024.105130

Kavousinejad, S., Ghazanfari, S., Manshadi, S. A. H., Biglar, N., Nahvi, G., Dalaie, K., Behnaz, M., Mirmohammadsadeghi, H., Tahmasbi, S., & Ebadifar, A. (2026). Artificial Intelligence–Based Multi-Stage System for Automated Angle’s Classification of Malocclusion from Intraoral Images in Orthodontics. Journal of Imaging Informatics in Medicine. https://doi.org/10.1007/s10278-025-01826-7

Dot, G., Chaurasia, A., Dubois, G., Savoldelli, C., Haghighat, S., Azimian, S., Taramsari, A. R., Sivaramakrishnan, G., Issa, J., Dubey, A., Schouman, T., & Gajny, L. (2024). DentalSegmentator: Robust open source deep learning-based CT and CBCT image segmentation. Journal of Dentistry, 147, 105130. https://doi.org/10.1016/j.jdent.2024.105130

Kavousinejad, S., Ghazanfari, S., Manshadi, S. A. H., Biglar, N., Nahvi, G., Dalaie, K., Behnaz, M., Mirmohammadsadeghi, H., Tahmasbi, S., & Ebadifar, A. (2026). Artificial Intelligence–Based Multi-Stage System for Automated Angle’s Classification of Malocclusion from Intraoral Images in Orthodontics. Journal of Imaging Informatics in Medicine. https://doi.org/10.1007/s10278-025-01826-7

Downloads

Published

2026-08-07

How to Cite

Cruzatt, H. C. ., Candelaria, M. N. ., Ramírez, N. Z. ., Gonzalez, D. S. ., Herrera, M. R. ., Machado, R. L. ., & Gonzaga, N. . (2026). Application of Deep Learning on Large-Scale Dental Imaging for Automated Diagnosis and Treatment Planning in Orthodontics and General Dentistry. American Journal of Medical Science and Innovation, 5(2), 46-54. https://doi.org/10.54536/ajmsi.v5i2.8208

Similar Articles

31-40 of 103

You may also start an advanced similarity search for this article.