Malaria Prevalence and Associated Risk Factors among Pregnant Women Attending the Prenatal Care Unit of the Ntoum Departmental Hospital (NDH), Northwest Gabon
DOI:
https://doi.org/10.54536/ajlsi.v4i1.4680Keywords:
Gabon, Malaria, Ntoum, Pregnant Women, PrevalenceAbstract
Malaria during pregnancy is a significant public health problem in endemic countries. This study aimed to determine the prevalence of malaria and associated risk factors among pregnant women attending the Departmental Hospital of Ntoum (Northwest Gabon) for prenatal care. A cross-sectional survey was conducted for 6 months (July to December 2024), among pregnant women attending the prenatal care unit of the Ntoum departmental Hospital (NDH). Pregnant women selected for the study were asked to complete a structured questionnaire. At the end of the interview, a nurse drew a blood sample in an EDTA tube. Malaria was detected by thick blood smear using the WHO method. A P-value < 0.05 was considered statistically significant. Blood samples were collected from 202 pregnant women. Malaria was diagnosed in 23.3%. Patients aged between 20 and 30 years (53.2%), with a gestation of 4 to 6 months (46.8%) and living in the first district of Ntoum city (70.2%) were the most infected with the disease. Most of these women had completed secondary education (87.2%) and were unemployed (68.1%). Fever and headache were the most frequently reported symptoms, accounting for 51.1% and 42.5% of cases, respectively. Women who slept under an insecticide-treated net or used insecticide spray were less prone to malaria infection; but, the difference was not significant (P˃0.05) In contrast, pregnant women who reported episodes of fever were significantly less likely to test positive to malaria (OR = 0.24 [0.09 - 0.61]; P =0.002). Among the women who tested positive, 83% had a low parasitemia. Plasmodium infection in the Komo Mondah department is high. The development of a malaria vaccine would make it possible to immunize all participants and thus reduce the spread of malaria worldwide.
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Abdou, L., Rabo, Y., Kailou, M. H. S., Assane, M. M., & Mahamane, A. (2024). Effets de la présence du Basilic (Ocimum basilicum L.) sur les insectes ravageurs du chou (Brassica oleracea L.) et sur le rendement de la culture dans la commune de Maïné-Soroa au Niger. International Journal of Biological and Chemical Sciences, 18(6), 2238-2249
Agyekum, T. P., Botwe, P. K., Arko-Mensah, J., Issah, I., Acquah, A. A., Hogarh, J. N., ... & Fobil, J. N. (2021). A systematic review of the effects of temperature on Anopheles mosquito development and survival: implications for malaria control in a future warmer climate. International journal of environmental research and public health, 18(14), 7255.
Ahadzie-Soglie, A., Addai-Mensah, O., Abaka-Yawson, A., Setroame, A. M., & Kwadzokpui, P. K. (2022). Prevalence and risk factors of malaria and anaemia and the impact of preventive methods among pregnant women: A case study at the Akatsi South District in Ghana. PLoS One, 17(7), e0271211.
Akono, P. N., Mbongue, R. S., Dadji, G. A. F., Tsila, H. G., Enama, L. O., Takap, F. N., ... & Mbida, J. A. M. (2022). Habitats larvaires d ‘Anopheles gambiae sl et mécanismes de résistance à Kribi (Cameroun). Médecine Tropicale et Santé Internationale, 2(4).
Ali, R. (2022). Malaria Prevalence among Pregnant Women in Relation to Parity, Gestation Period and Age in Gombe, North Eastern Nigeria. Journal of Applied Sciences and Environmental Management, 26(6), 1063-1066.
Almaw, A., Yimer, M., Alemu, M., Belay, H., Alebachew, M., Abeje, G., ... & Tegegne, B. (2024). Prevalence of clinical malaria and associated symptoms in pregnant women at Hamusit health center, Northwest Ethiopia. Heliyon, 10(14).
Almaw, A., Yimer, M., Alemu, M., & Tegegne, B. (2022). Prevalence of malaria and associated factors among symptomatic pregnant women attending antenatal care at three health centers in north-west Ethiopia. PLoS One, 17(4), e0266477.
Al-Quhaiti, M. A., Abdul-Ghani, R., Mahdy, M. A., & Assada, M. A. (2022). Malaria among under-five children in rural communities of Al-Mahweet governorate, Yemen. Malaria Journal, 21(1), 344.
Bah, M. S. (2020). The relationship between malaria status in under-five children and some household demographic, socioeconomic and environmental factors associated with the disease in Sierra Leone.
Bihingoyi, M. T. Paludisme sur grossesse: cas du service de gynéco-obstétrique de l’hôpital général de référence de Walungu: à propos de 40 cas.(2011, 2012) (Doctoral dissertation, Thèse med] Université évangélique en Afrique/UEA RDC 2013. p102).
Botolahy, Z. A., Randriambelomanana, J. A., Imbara, E., Rakotoarisoa, H., & Andrianampanalinarivo, H. R. (2011). Aspects du paludisme à Plasmodium falciparum pendant la grossesse selon les cas observés au CHU de Toamasina Madagascar. Revue d’Anesthésie-Réanimation et de Médecine d’Urgence, 3(1), 23-26.
Chaves, L. S. M., Hamer, G. L., Laporta, G. Z., Sallum, M. A. M., & Biondi, G. F. (2021). Anthropogenic landscape decreases mosquito biodiversity and drives malaria vector proliferation in the Amazon rainforest. PLOS ONE, 16(1), e0245087.
Delbaere, I., Verbiest, S., & Tydén, T. (2020). Knowledge about the impact of age on fertility: a brief review. Upsala journal of medical sciences, 125(2), 167-174.
Diallo, D., Diakité, C., Mounkoro, P. P., Sangaré, D., Graz, B., Falquet, J., & Giani, S. (2007). La prise en charge du paludisme par les thérapeutes traditionnels dans les aires de santé de Kendié (Bandiagara) et de Finkolo (Sikasso) au Mali. Mali Med, 12, 1-8.
Diarra, S. S., Kayentao, K., Diawara, S. I., Telly, N., Soumounou, F., Niangaly, M., ... & Doumbia, S. (2022). Les Socio-clinical factors associated with malaria during pregnancy in San health district, Mali: Caractéristiques socio-cliniques de la femme associées au PPG au Mali. Health Sciences and Disease, 23(12).
Direction Générale de la Statistique. (2015). Résultats globaux du Recensement Général de la Population et des Logements de 2013 du Gabon. Libreville.
Direction Générale de la Statistique (DGS), & ICF. (2022). Enquête démographique et de santé au Gabon, 2019–2021. Libreville, Gabon & Rockville, MD, USA.
Dufera, M., Dabsu, R., & Tiruneh, G. (2020). Assessment of malaria as a public health problem in and around Arjo Didhessa sugar cane plantation area, Western Ethiopia. BMC public health, 20, 1-10.
Dwumfour, C. K., Bam, V. B., Owusu, L. B., Poku, C. A., Kpabitey, R. D., Aboagye, P., & Ibrahim, A. S. (2023). Prevalence and determinants of malaria infection among pregnant women attending antenatal clinic in Ejisu government hospital in Ghana: A cross-sectional study. PLoS One, 18(10).
Fu, G. (2024). Epidemiological patterns of mosquito-borne diseases globally. Journal of Mosquito Research, 14.
Idris Nour, A. A., Karrar, T. I., Kebayer, M. H. A., Abd Elwahid Mohamed, N. A., Mohammed Zarroug, K. S., Ismael Hajrhma Mohammedahmed, H., & Salah Mohamed Ahmed, M. A. (2023). Prevalence of malaria parasite among pregnant women attending to Saudi Kassala Teaching hospital in Kassala state, Eastern Sudan. Journal of Tropical Medicine, 2023(1), 2289552.
Kawuki, J., Donkor, E., Gatasi, G., & Nuwabaine, L. (2023). Mosquito bed net use and associated factors among pregnant women in Rwanda: a nationwide survey. BMC Pregnancy and Childbirth, 23(1), 419.
Kenguele, H. M., Meye, B., Ndong, T., & Mickala, P. (2022). Prevalence of haemoparasites among blood donors attending the regional hospital Center of Franceville (Southern Gabon). J Infect Dis Epidemiol, 8(7), 270.
Kodio, O., Diakité, I., Koité, N., Ly, B. A., & Kassogue, A. (2023). Comparaison des coûts du traitement du paludisme en biomédecine et en médecine traditionnelle à Niono (Mali). Revue Internationale des Sciences Médicales (Abidjan), 114, 114–121.
Mabiala, A. N., Obame-Nkoghe, J., Bisseye, C., Tanga, T., & Mombo, L. E. (2021). Connaissances et méthodes de lutte contre le paludisme au sein des ménages de la cité minière de Moanda en zone semi-rurale au Sud-Est Gabon. Journal of Applied Biosciences, 159(1), 16411-16419
Mahaman Toudou B.I., Ali D., et Hima. M.K. (2021). Pratiques et risques sanitaires associés aux produits anti-moustiques utilisés dans la lutte anti-vectorielle dans la ville de Niamey au Niger. Afrique SCIENCE 19(5) 136 – 148
Mangusho, C., Mwebesa, E., Izudi, J., Aleni, M., Dricile, R., Ayiasi, R. M., & Legason, I. D. (2023). High prevalence of malaria in pregnancy among women attending antenatal care at a large referral hospital in northwestern Uganda: a cross-sectional study. Plos one, 18(4), e0283755.
Mabiala, A. N., Obame-Nkoghe, J., Bisseye, C., Tanga, T., & Mombo, L. E. (2021). Connaissances et méthodes de lutte contre le paludisme au sein des ménages de la cité minière de Moanda en zone semi-rurale au Sud-Est Gabon. Journal of Applied Biosciences, 159(1), 16411-16419.
Mbouloungou, A., Koumba, A. A., Mombo, J. B., Iyangui, N. N., Mavoungou, J. F., & Djeki, J. (2019). Géographie du paludisme dans la région de Libreville-Owendo-Akanda, Gabon. European Scientific Journal, 15(2), 362-382.
Meye, B., Alame-Emane, A. K., Kenguele, H. M., Mve, R. E. A., Ondo, J. P., & Engonga, L. C. O. (2024). Malaria prevention practices among patients attending the NTOUM departmental hospital, Northwest Gabon. Open Access Research Journal of Biology and Pharmacy, 11(1), 073-080.
Namwera, O., Odongo, A., & Mogere, D. (2025). Knowledge and awareness on signs, symptoms, and complications of malaria during pregnancy among pregnant women: Case of Kamuzu Central Hospital, Malawi. Academic Journal of Health Systems and Reforms, 13(1), 137–147.
Nankabirwa, J., Brooker, S. J., Clarke, S. E., Fernando, D., Gitonga, C. W., Schellenberg, D., & Greenwood, B. (2014). Malaria in school‐age children in Africa: an increasingly important challenge. Tropical medicine & international health, 19(11), 1294-1309.
Nguefack, C. T. (2018). Facteurs déterminants de l’âge gestationnel à la première consultation prénatale à Douala (Cameroun). Journal de la SAGO (Gynécologie–Obstétrique et Santé de la Reproduction), 19(1).
Obossou, A. A. A., Sidi, R. I., Atade, R. S., Vodouhe, M. V., Klikepezo, R., Salmane, A., ... & Salifou, K. (2024). Fréquence et Facteurs Associés au Paludisme chez les Femmes Enceintes dans les Maternités Périphériques Publiques de Parakou (Bénin) en 2018. ESI Preprints, 20(3).
Ogomaka, I. A., & Obeagu, E. I. (2021). Malaria in pregnancy amidst possession of insecticide treated bed nets (ITNs) in Orlu LGA of Imo State, Nigeria. Journal of Pharmaceutical Research International, 33(41B), 380-6.
Okiring, J., Olwoch, P., Kakuru, A., Okou, J., Ochokoru, H., Ochieng, T. A., ... & Tusting, L. S. (2019). Household and maternal risk factors for malaria in pregnancy in a highly endemic area of Uganda: a prospective cohort study. Malaria journal, 18, 1-9.
Okoroiwu, G. I. A. (2023). Prevalence of malaria and associated risk factors in pregnant women in mbaitoli local government area, South-east Nigeria. African Journal of Biomedical Research, 26(2), 167-172.
Okoyo, C., Githinji, E., Muia, R. W., Masaku, J., Mwai, J., Nyandieka, L., ... & Kanyi, H. M. (2021). Assessment of malaria infection among pregnant women and children below five years of age attending rural health facilities of Kenya: A cross-sectional survey in two counties of Kenya. Plos one, 16(9), e0257276.
Organisation mondiale de la santé –Gabon. (2023). Rapport annuel 2023.
Oyerogba, O. P., Adedapo, A., Awokson, T., Odukogbe, A. T., & Aderinto, N. (2023). Prevalence of malaria parasitaemia among pregnant women at booking in Nigeria. Health Science Reports, 6(6), e1337.
Pamba, R., Sevidzem, S. L., Koumba, A. A., Zinga-Koumba, C. R., Ovono, A. P. M., MintsaNguema, R., Mavoungou, J. F., Mbouloungou, A., M’Foubou Kassa, F., & Kutomy, P. O. O. (2021). Preventive measures against the vectors of malaria in Akanda, southwest Gabon: Knowledge, attitudes, practices, and beliefs. European Scientific Journal, ESJ, 17(21), 169.
Ramharter, M., Schuster, K., Bouyou-Akotet, M. K., Adegnika, A. A., Schmits, K., Mombo-Ngoma, G., ... & Kremsner, P. G. (2007). Malaria in pregnancy before and after the implementation of a national IPTp program in Gabon. The American Journal of Tropical Medicine and Hygiene, 77(3), 418–422.
Rek, J., Musiime, A., Zedi, M., Otto, G., Kyagamba, P., Asiimwe Rwatooro, J., ... & Krezanoski, P. J. (2020). Non-adherence to long-lasting insecticide treated bednet use following successful malaria control in Tororo, Uganda. PloS one, 15(12), e0243303.
Rouamba, T., Samadoulougou, S., Ouédraogo, M., Hien, H., Tinto, H., & Kirakoya-Samadoulougou, F. (2021). Asymptomatic malaria and anaemia among pregnant women during high and low malaria transmission seasons in Burkina Faso: household-based cross-sectional surveys in Burkina Faso, 2013 and 2017. Malaria Journal, 20(1), 211
Salissou, I., Moustapha, L. M., Yerima, B., Alkassoum, I., Hadiza, D., & Ibrahim, M. L. (2016). Perception de la chimioprévention du paludisme saisonnier au Niger. International Journal of Biological and Chemical Sciences, 10(6), 2710-2715.
Santara, M. (2024). Paludisme chez les femmes enceintes: Épidémiologie, prise en charge et pronostic au centre de santé de référence de la commune II de Bamako [Doctoral dissertation, Université des Sciences, des Techniques et des Technologies de Bamako (USTTB)].
Steketee, Richard W., et al. (2001).The burden of malaria in pregnancy in malaria-endemic areas. The Intolerable Burden of Malaria: A New Look at the Numbers. American Journal of Tropical Medicine and Hygiene., 64(1)
Tahita, M. C., Tinto, H., Menten, J., Ouedraogo, J. B., Guiguemde, R. T., van Geertruyden, J. P., ... & D’Alessandro, U. (2013). Clinical signs and symptoms cannot reliably predict Plasmodium falciparum malaria infection in pregnant women living in an area of high seasonal transmission. Malaria journal, 12, 1-7.
Tonda, M. (2024). Sodomythes, homosexualité et valeur de la vie. Les limites de la « restauration de la dignité » au lendemain du coup d’État au Gabon. Politique africaine, 174(2), 69-88
Verhoeff, F. H., Brabin, B. J., Hart, C. A., Chimsuku, L., Kazembe, P., & Broadhead, R. L. (1999). Increased prevalence of malaria in HIV‐infected pregnant women and its implications for malaria control. Tropical Medicine & International Health, 4(1), 5-12.
World Health Organization. (2019). World malaria report 2019. World Health Organization.
World Health Organization. (2022). World malaria report 2022. World Health Organization.
World Health Organization. (2023). World malaria report 2023. World Health Organization.
World Health Organization. (2024). World malaria report 2024. World Health Organization.
Yameogo, R. B. (2023). Facteurs associes au retard à la consultation prénatale du premier trimestre (CPN 1) chez les femmes enceintes dans le district sanitaire de Koupela (Burkina Faso). Journal de la sago (Gynécologie–Obstétrique et Santé de la Reproduction), 24(2).
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Copyright (c) 2025 Bourdettes Meye, Hilaire Moundounga Kenguele, Ludjer Mpiga Ekambou, Strédice Maguinga Guitouka, Robert Eya’ama Mve, Kevin Alame Emane, Joseph Privat Ondo, Louis Clément Obame Engonga
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