Clinical Diagnosis and Management of Diseases in Semi-Captive Bonobos (Pan paniscus) at Lola Ya Bonobo Sanctuary, Kinshasa, DRC
DOI:
https://doi.org/10.54536/jwc.v2i1.7154Keywords:
Bonobo, Clinical Pathology, Democratic Republic of Congo, Disease Management, Pan Paniscus, SanctuaryAbstract
The bonobo (Pan paniscus) is an endemic great ape of the Democratic Republic of Congo and is increasingly threatened by habitat loss, illegal hunting, and diseases. Veterinary surveillance in sanctuaries is therefore essential for conservation. This retrospective study describes the main clinical conditions diagnosed and managed in semi-captive bonobos at the Lola Ya Bonobo Sanctuary (Kinshasa, DRC) between 2020 and 2023. Clinical records from the sanctuary veterinary service were reviewed, and disease frequencies were analyzed by year and age class. A total of 358 clinical cases were recorded. Gastrointestinal disorders, particularly diarrhea, predominated in 2020 and 2022, whereas respiratory conditions, mainly cough, were most frequent in 2021 and 2023. Juveniles (0-8 years) were consistently the most affected age group. Treatments relied primarily on human pharmaceutical products adapted for veterinary use, and all affected bonobos recovered, with no mortality recorded during the study period. These findings highlight the importance of continuous clinical monitoring and appropriate therapeutic management for the health and conservation of bonobos, such
References
Altizer, S., Nunn, C. L., Thrall, P. H., Gittleman, J. L., Antonovics, J., Cunningham, A. A., Dobson, A. P., Ezenwa, V., Jones, K. E., Pedersen, A. B., Poss, M., & Pulliam, J. R. C. (2003). Social organization and parasite risk in mammals: Integrating theory and empirical studies. Annual Review of Ecology, Evolution, and Systematics, 34, 517-547. https://doi.org/10.1146/annurev.ecolsys.34.030102.151725
Ashford, R. W., & Crewe, W. (2003). The parasites of primates. Advances in Parasitology, 54, 1-92. https://doi.org/10.1016/S0065-308X(03)54001-5
Brook, C. E., & Dobson, A. P. (2015). Bats as ‘special’ reservoirs for emerging zoonotic pathogens. Trends in Ecology & Evolution, 30(3), 172-180. https://doi.org/10.1016/j.tree.2014.12.004
Calvignac-Spencer, S., Leendertz, F. H., Gillespie, T. R., & Leendertz, S. A. J. (2012). Infectious disease dynamics in primate populations. Current Opinion in Virology, 2(4), 359–364. https://doi.org/10.1016/j.coviro.2012.02.012
Chapman, C. A., & Gillespie, T. R. (2008). Behavioral ecology of parasitism in primates: A review. Trends in Parasitology, 24(11), 529-536. https://doi.org/10.1016/j.pt.2008.07.005
Chapman, C. A., Speirs, M. L., Gillespie, T. R., Holland, T., & Austad, K. M. (2006). Life on the edge: Gastrointestinal parasites from the forest edge and interior primate groups. International Journal of Primatology, 27(5), 123-138. https://doi.org/10.1007/s10764-006-9057-z
Cleaveland, S., Laurenson, M. K., & Taylor, L. H. (2001). Diseases of humans and their domestic mammals: Pathogen characteristics, host range and the risk of emergence. Philosophical Transactions of the Royal Society B: Biological Sciences, 356(1411), 991-999. https://doi.org/10.1098/rstb.2001.0889
Daszak, P., Cunningham, A. A., & Hyatt, A. D. (2000). Emerging infectious diseases of wildlife-Threats to biodiversity and human health. Science, 287(5452), 443-449. https://doi.org/10.1126/science.287.5452.443
Fruth, B., & Hohmann, G. (2006). Population densities of bonobos (Pan paniscus) in the Lomako Forest, Democratic Republic of Congo. American Journal of Primatology, 68(10), 1027-1040. https://doi.org/10.1002/ajp.20290
Gillespie, T. R. (2006). Noninvasive assessment of gastrointestinal parasite infections in free-ranging primates. International Journal for Parasitology, 36(10-11), 1033-1043. https://doi.org/10.1016/j.ijpara.2006.02.009
Gillespie, T. R., & Chapman, C. A. (2008). Forest fragmentation, the decline of an endangered primate, and changes in host-parasite interactions relative to an unfragmented forest. Conservation Biology, 22(4), 1022-1030. https://doi.org/10.1111/j.1523-1739.2008.00978.x
Goldberg, T. L., Gillespie, T. R., Rwego, I. B., Estoff, E. L., & Chapman, C. A. (2008). Forest fragmentation as cause of bacterial transmission among nonhuman primates, humans, and livestock, Uganda. Emerging Infectious Diseases, 14(9), 1375-1382. https://doi.org/10.3201/eid1409.071196
Haydon, D. T., Cleaveland, S., Taylor, L. H., & Laurenson, M. K. (2002). Identifying reservoirs of infection: A conceptual and practical challenge. Ecology Letters, 5(4), 584-595. https://doi.org/10.1046/j.1461-0248.2002.00364.x
Hohmann, G., & Fruth, B. (2003). Culture in bonobos? Between-species and within-species variation in behavior. Current Anthropology, 44(4), 563-571. https://doi.org/10.1086/377649
Hotez, P. J., Brindley, P. J., Bethony, J. M., King, C. H., Pearce, E. J., & Jacobson, J. (2008). Helminth infections: The great neglected tropical diseases. The Lancet, 371(9612), 203-213. https://doi.org/10.1016/S0140-6736(07)61921-6
Huffman, M. A. (2003). Primate self-medication and disease control. Evolutionary Anthropology, 12(4), 185-194. https://doi.org/10.1002/evan.10105
Karesh, W. B., Dobson, A., Lloyd-Smith, J. O., Lubroth, J., Dixon, M. A., Bennett, M., Aldrich, S., Harrington, T., Formenty, P., Loh, E. H., Machalaba, C. C., Thomas, M. J., & Heymann, D. L. (2012). Ecology of zoonoses: Natural and unnatural histories. Revue Scientifique et Technique, 31(1), 23-38. https://doi.org/10.20506/rst.31.1.2101
Köndgen, S., Kühl, H., N’Goran, P. K., Walsh, P. D., Schenk, S., Ernst, N., Biek, R., Formenty, P., Mätz-Rensing, K., Schweiger, B., Junglen, S., Ellerbrok, H., Nitsche, A., Briese, T., Lipkin, W. I., Pauli, G., Boesch, C., & Leendertz, F. H. (2008). Pandemic human viruses cause decline of endangered great apes. Current Biology, 18(4), 260–264. https://doi.org/10.1016/j.cub.2008.01.012
Leendertz, F. H., Pauli, G., Maetz-Rensing, K., Boardman, W., Nunn, C. L., Ellerbrok, H., Jensen, S. A., Junglen, S., & Boesch, C. (2006). Pathogens as drivers of population declines: The importance of systematic monitoring in great apes and other threatened mammals. Biological Conservation, 131(2), 325-337. https://doi.org/10.1016/j.biocon.2006.05.002
Leendertz, F. H., Gogarten, J. F., Düx, A., Calvignac-Spencer, S., & Leendertz, S. A. J. (2016). Assessing the evidence supporting fruit bats as the primary reservoirs for Ebola viruses. Nature Reviews Microbiology, 14(9), 591-604. https://doi.org/10.1038/nrmicro.2016.72
Makouloutou, P., Akoua-Koffi, C., Hadjivassiliou, M., & Kouassi, S. (2014). Intestinal parasites of wild primates in Central Africa. Parasitology Research, 113(7), 2545-2555. https://doi.org/10.1007/s00436-014-3917-6
McMichael, A. J. (2004). Environmental and social influences on emerging infectious diseases: Past, present and future. New England Journal of Medicine, 351(21), 2069-2071. https://doi.org/10.1056/NEJMp048235
Murray, S., Stem, C., Boudreau, B., & Goodall, J. (2011). Causes of morbidity and mortality in captive chimpanzees (Pan troglodytes). Journal of Medical Primatology, 40(6), 349-356. https://doi.org/10.1111/j.1600-0684.2011.00488.x
Nizeyi, J. B., Sebunya, D., Dasilva, A. J., Cranfield, M. R., & Graczyk, T. K. (2002). Cryptosporidium sp. and Giardia sp. infections in mountain gorillas. Emerging Infectious Diseases, 8(4), 418-421. https://doi.org/10.3201/eid0804.010389
Nunn, C. L., & Altizer, S. M. (2006). Infectious diseases in primates: Behavior, ecology and evolution. Oxford University Press.
Oates, J. F. (2013). Primate conservation. Cambridge University Press.
Palacios, G., Lowenstine, L. J., Cranfield, M. R., Gilardi, K. V. K., Spelman, L., Lukasik-Braum, M., Kinani, J.-F., Mudakikwa, A., Nyirakaragire, E., Bussetti, A. V., Savji, N., Hutchison, S., Egholm, M., Lipkin, W. I., & Briese, T. (2011). Human metapneumovirus infection in wild mountain gorillas. Emerging Infectious Diseases, 17(4), 711-713. https://doi.org/10.3201/eid1704.100883
Pedersen, A. B., & Fenton, A. (2007). Emphasizing parasitology in conservation biology. Trends in Ecology & Evolution, 22(3), 133-139. https://doi.org/10.1016/j.tree.2006.11.006
Salyer, S. J., Silver, R., Simone, K., & Barton Behravesh, C. (2017). Prioritizing zoonoses for global health capacity building. PLoS ONE, 12(12), e0178362. https://doi.org/10.1371/journal.pone.0178362
Sleeman, J. M., DeLiberto, T. J., Nguyen, N., & Davenport, K. (2010). Zoo and wildlife medicine in conservation. Revue Scientifique et Technique, 29(2), 259-271. https://doi.org/10.20506/rst.29.2.1980
Thompson, R. C. A. (2004). The zoonotic significance and molecular epidemiology of Giardia. Clinical Microbiology Reviews, 17(3), 483-509. https://doi.org/10.1128/CMR.17.3.483-509.2004
Woodford, M. H., Butynski, T. M., & Karesh, W. B. (2002). Habituating the great apes: The disease risks. Oryx, 36(2), 153-160. https://doi.org/10.1017/S003060530200022X
Wolfe, N. D., Daszak, P., Kilpatrick, A. M., & Burke, D. S. (2005). Bushmeat hunting, deforestation, and prediction of zoonotic disease emergence. Emerging Infectious Diseases, 11(12), 1822-1827. https://doi.org/10.3201/eid1112.040789
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Copyright (c) 2026 Paulin Mungongo Mayama, Mukamba Jonas, Pomme Francis, Mbiala Vodiasilua, Curé Georges Tshilenge, Masuku Masky, Bha Nsekene, Diafuka Saila-Ngita, Kiela Jenny, Mulumba Mfumu-Kazadi
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