Potent Antioxidant Agents: Dithiocarbamates of Ω-Substituted (2-Naphthyloxy) Alkanes

Authors

  • Sadaf Zaidi Department of Applied Chemistry, Amity School of Applied Sciences, Amity University Uttar Pradesh (AUUP), Lucknow Campus, Lucknow-226028, U. P. India
  • Devdutt Chaturvedi Department of Chemistry, School of Physical & Material Sciences, Mahatma Gandhi Central University (MGCU), Motihari, Bihar, India
  • Nitin Srivastava Department of Applied Chemistry, Amity School of Applied Sciences, Amity University Uttar Pradesh (AUUP), Lucknow Campus, Lucknow-226028, U. P. India
  • Manisha Shukla cDepartment of Chemistry, Babu Banarasi Das National Technology & Management, Lucknow-227105, U. P India

DOI:

https://doi.org/10.54536/ajcp.v2i2.1686

Keywords:

Amines, Antioxidant, Dithiocarbamates, Condensation, Catalyst

Abstract

A series of dithiocarbamates of ω-substituted (2-naphthyloxy) alkanes (4-48) was tested for antioxidant activity by radicals 2,2-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) assay, DPPH assay (1,1-diphenyl-2-picryl-hydrazyl), O2. (NET) assay and ROO. (TRAP) assay against curcumin and vitamin C as standard drugs. Most of these compounds have shown promising activities, such compounds are 11, 12, 13, 25, 26, 27, 28, 41, 42, and 43. The series was synthesized by the condensation reaction of 2-(2-chloro-alkoxy)-naphthalene with different types of aliphatic, alicyclic, aromatic, heterocyclic primary, as well as secondary amines to develop dithiocarbamates of ω-substituted (2-naphthyloxy) alkanes.

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Author Biographies

Devdutt Chaturvedi, Department of Chemistry, School of Physical & Material Sciences, Mahatma Gandhi Central University (MGCU), Motihari, Bihar, India

Head of Department

Nitin Srivastava, Department of Applied Chemistry, Amity School of Applied Sciences, Amity University Uttar Pradesh (AUUP), Lucknow Campus, Lucknow-226028, U. P. India

Assistant Professor

Manisha Shukla, cDepartment of Chemistry, Babu Banarasi Das National Technology & Management, Lucknow-227105, U. P India

Head of Chemistry

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Published

2023-07-13

How to Cite

Zaidi, S., Chaturvedi, D., Srivastava, N., & Shukla, M. (2023). Potent Antioxidant Agents: Dithiocarbamates of Ω-Substituted (2-Naphthyloxy) Alkanes. American Journal of Chemistry and Pharmacy, 2(2), 86–98. https://doi.org/10.54536/ajcp.v2i2.1686

Issue

Vol. 2 No. 2 (2023): American Journal of Chemistry and Pharmacy

Section

Research Articles

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Copyright (c) 2023 Sadaf Zaidi, Devdutt Chaturvedi, Nitin Srivastava, Manisha Shukla

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