Synthesis, Characterisation and Comparative Study of Hydrogel and Nanogels of Psyllium

Authors

  • Suman Kumar Department of Chemistry, A. P. Goyal Shimla University Shimla, India
  • Rohini Dharela School of Sciences, A. P. Goyal Shimla University, Shimla, Himachal Pradesh, India
  • Ghanshyam S. Chauhan Emeritus Scientist, Department of Chemistry, Himachal Pradesh University, India

Keywords:

Hydrogel, Nanogel, Psyllium, Swelling

Abstract

Natural polysaccharides are being explored as the matrices for attaining speciality materials for pharmaceutical, medicinal and environmental applications via chemical modification such as grafting. Psyllium polysaccharide-based hydrogels and nanogels have potential biomedical and water purification applications due to their advantageous properties such as stimulus responsiveness, biocompatibility, target drug delivery and stability. The present study aims to synthesise hydrogel and nanogels of psyllium and attain comparative data for the two to undermine their potential applications. Psyllium– cl –N,N–MBAm–poly(AAm) hydrogel (Psy-MBAm-AAm – hg) and Psyllium– cl –N,N–MBAm–poly(AAm) nanogel (Psy-MBAm-AAm – ng) were synthesised by grafting acrylamide (AAm) onto psyllium using ammonium persulphate (APS) as a free radical initiator in a redox system where N, N-methylene bisacrylamide acted as a crosslinker. The comparative study of synthesised gels was carried out by studying swelling characteristics at acidic and basic pH (7 and 4) and at varied temperatures for both matrices. The synthesised hydrogel and nanogels were subjected to characterisation by Fourier transform infrared spectroscopy (FTIR), Field Emission Scanning Electron Microscopy (FESEM), and Zeta Potential Analysis to get evidence for successful synthesis and nanogel formation.

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Published

2023-03-15

How to Cite

Kumar, S., Dharela, R., & Chauhan, G. S. (2023). Synthesis, Characterisation and Comparative Study of Hydrogel and Nanogels of Psyllium. American Journal of Innovation in Science and Engineering, 2(1), 43–50. Retrieved from https://journals.e-palli.com/home/index.php/ajise/article/view/1289

Issue

Vol. 2 No. 1 (2023): American Journal of Innovation in Science and Engineering

Section

Research Articles

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Copyright (c) 2023 Suman Kumar, Rohini Dharela, Ghanshyam S. Chauhan

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This work is licensed under a Creative Commons Attribution 4.0 International License.