Recurrent Symptomatic Renal Stones Managed by Repeat Open Nephrolithotomy in a Rural Kenyan Hospital

Authors

  • Vonwicks C. Onyango Department of Medicine, St. Joseph RV Hospital, Gilgil, Nakuru, County, Kenya https://orcid.org/0009-0004-6791-8809
  • Winston O. Makanga Department of Surgery, St. Joseph Rift Valley Hospital, Gilgil, Nakuru County, Kenya
  • Ali J. Kariuki Department of Surgery, St. Joseph Rift Valley Hospital, Gilgil, Nakuru County, Kenya
  • Boniface M. Kioko Department of Anesthesia, St. Joseph Rift Valley Hospital, Gilgil, Nakuru County, Kenya
  • Mumina D. Dido Department of Anesthesia, St. Joseph Rift Valley Hospital, Gilgil, Nakuru County, Kenya
  • Thomas M. Kamau Department of Radiography, St. Joseph Rift Valley Hospital, Gilgil, Nakuru County, Kenya
  • William C. Fryda Department of Medicine, St. Joseph RV Hospital, Gilgil, Nakuru, County, Kenya

DOI:

https://doi.org/10.54536/ajmsi.v3i2.2896

Keywords:

Kidney Stone Disease, Nephrolithiasis, Urolithiasis, Renal Calculi, Calcium Oxalate Stones, Recurrent Kidney Stones, Nephrolithotomy, Kenya

Abstract

Kidney stone disease (nephrolithiasis, urolithiasis, and renal calculi) is characterized by the formation of both symptomatic and asymptomatic obstructive and non-obstructive calculi in the urinary tract. Calcium oxalate stones are the most common type, related to the consumption of large amounts of oxalate-rich foods. Other stones are made of calcium phosphate, hydroxyapatite, uric acid, cystine, and struvite. Urolithiasis is increasingly being reported in both urban and rural Kenya. Minimally invasive surgical treatment of symptomatic stones is the current standard of care, but open nephrolithotomy remains a viable option in selected patients. Nonetheless, the rates of stone recurrence remain high, increasing from 15% at 1 year to 50% at 10 years due to multifactorial risk factors. In this study, we report the case of a rural Kenyan patient who underwent the third open nephrolithotomy in 10 years for recurrent symptomatic stones and whose biochemical analysis has guided subsequent preventative dietary efforts against stone recurrence.

Downloads

Download data is not yet available.

References

Alelign, T., & Petros, B. (2018). Kidney Stone Disease: An Update on Current Concepts. Adv Urol, 2018, 3068365. https://doi.org/10.1155/2018/3068365

Çakici Ö, U., Ener, K., Keske, M., Altinova, S., Canda, A. E., Aldemir, M., & Ardicoglu, A. (2017). Open stone surgery: a still-in-use approach for complex stone burden. Cent European J Urol, 70(2), 179-184. https://doi.org/10.5173/ceju.2017.1205

Chewcharat, A., & Curhan, G. (2021). Trends in the prevalence of kidney stones in the United States from 2007 to 2016. Urolithiasis, 49(1), 27-39. https://doi.org/10.1007/s00240-020-01210-w

Coe, F. L., Worcester, E. M., & Evan, A. P. (2016). Idiopathic hypercalciuria and formation of calcium renal stones. Nat Rev Nephrol, 12(9), 519-533. https://doi.org/10.1038/nrneph.2016.101

Daudon, M., Frochot, V., Bazin, D., & Jungers, P. (2018). Drug-Induced Kidney Stones and Crystalline Nephropathy: Pathophysiology, Prevention and Treatment. Drugs, 78(2), 163-201. https://doi.org/10.1007/s40265-017-0853-7

Dawson, C. H., & Tomson, C. R. (2012). Kidney stone disease: pathophysiology, investigation and medical treatment. Clin Med (Lond), 12(5), 467-471. https://doi.org/10.7861/clinmedicine.12-5-467

Dhayat, N. A., Bonny, O., Roth, B., Christe, A., Ritter, A., Mohebbi, N., Faller, N., Pellegrini, L., Bedino, G., Venzin, R. M., Grosse, P., Hüsler, C., Koneth, I., Bucher, C., Giorno, R. D., Gabutti, L., Mayr, M., Odermatt, U., Buchkremer, F., . . . Fuster, D. G. (2023). Hydrochlorothiazide and Prevention of Kidney-Stone Recurrence. New England Journal of Medicine, 388(9), 781-791. https://doi.org/doi:10.1056/NEJMoa2209275

El-Husseiny, T., & Buchholz, N. (2012). The role of open stone surgery. Arab J Urol, 10(3), 284-288. https://doi.org/10.1016/j.aju.2012.03.004

Ferraro, P. M., Curhan, G. C., D’Addessi, A., & Gambaro, G. (2017). Risk of recurrence of idiopathic calcium kidney stones: analysis of data from the literature. J Nephrol, 30(2), 227-233. https://doi.org/10.1007/s40620-016-0283-8

Ferraro, P. M., Taylor, E. N., & Curhan, G. C. (2024). 24-Hour Urinary Chemistries and Kidney Stone Risk. Am J Kidney Dis. https://doi.org/10.1053/j.ajkd.2024.02.010

Gamage, K. N., Jamnadass, E., Sulaiman, S. K., Pietropaolo, A., Aboumarzouk, O., & Somani, B. K. (2020). The role of fluid intake in the prevention of kidney stone disease: A systematic review over the last two decades. Turk J Urol, 46(Supp. 1), S92-s103. https://doi.org/10.5152/tud.2020.20155

Khan, S. R., Pearle, M. S., Robertson, W. G., Gambaro, G., Canales, B. K., Doizi, S., Traxer, O., & Tiselius, H. G. (2016). Kidney stones. Nat Rev Dis Primers, 2, 16008. https://doi.org/10.1038/nrdp.2016.8

Lieske, J. C., Rule, A. D., Krambeck, A. E., Williams, J. C., Bergstralh, E. J., Mehta, R. A., & Moyer, T. P. (2014). Stone composition as a function of age and sex. Clin J Am Soc Nephrol, 9(12), 2141-2146. https://doi.org/10.2215/cjn.05660614

Mitchell, T., Kumar, P., Reddy, T., Wood, K. D., Knight, J., Assimos, D. G., & Holmes, R. P. (2019). Dietary oxalate and kidney stone formation. Am J Physiol Renal Physiol, 316(3), F409-f413. https://doi.org/10.1152/ajprenal.00373.2018

Musau, P. (2010). Urolithiasis--an emerging health problem in Kenya. East Afr Med J, 87(10), 393-394.

Ngugi, P. M., Magoha, G. A., & Kiptoon, D. (2010). Urolithiasis in Nairobi, Kenya. East Afr Med J, 87(10), 395-399.

Owino, C., Mutugi, A., & Tang, J. (2023). Hyperoxaluria - A Major Metabolic Risk for Kidney Stone Disease. R I Med J (2013), 106(11), 14-19.

Pearle, M. S., Goldfarb, D. S., Assimos, D. G., Curhan, G., Denu-Ciocca, C. J., Matlaga, B. R., Monga, M., Penniston, K. L., Preminger, G. M., Turk, T. M., & White, J. R. (2014). Medical management of kidney stones: AUA guideline. J Urol, 192(2), 316-324. https://doi.org/10.1016/j.juro.2014.05.006

Prezioso, D., Strazzullo, P., Lotti, T., Bianchi, G., Borghi, L., Caione, P., Carini, M., Caudarella, R., Ferraro, M., Gambaro, G., Gelosa, M., Guttilla, A., Illiano, E., Martino, M., Meschi, T., Messa, P., Miano, R., Napodano, G., Nouvenne, A., . . . Zattoni, F. (2015). Dietary treatment of urinary risk factors for renal stone formation. A review of CLU Working Group. Arch Ital Urol Androl, 87(2), 105-120. https://doi.org/10.4081/aiua.2015.2.105

Rodríguez, D., & Sacco, D. E. (2015). Minimally Invasive Surgical Treatment for Kidney Stone Disease. Advances in Chronic Kidney Disease, 22(4), 266-272. https://doi.org/https://doi.org/10.1053/j.ackd.2015.03.005

Scales, C. D., Jr., Smith, A. C., Hanley, J. M., & Saigal, C. S. (2012). Prevalence of kidney stones in the United States. Eur Urol, 62(1), 160-165. https://doi.org/10.1016/j.eururo.2012.03.052

Sorensen, M. D. (2014). Calcium intake and urinary stone disease. Transl Androl Urol, 3(3), 235-240. https://doi.org/10.3978/j.issn.2223-4683.2014.06.05

Tsujihata, M. (2008). Mechanism of calcium oxalate renal stone formation and renal tubular cell injury. Int J Urol, 15(2), 115-120. https://doi.org/10.1111/j.1442-2042.2007.01953.x

Türk, C., Petřík, A., Sarica, K., Seitz, C., Skolarikos, A., Straub, M., & Knoll, T. (2016). EAU Guidelines on Diagnosis and Conservative Management of Urolithiasis. Eur Urol, 69(3), 468-474. https://doi.org/10.1016/j.eururo.2015.07.040

Vaughan, L. E., Enders, F. T., Lieske, J. C., Pais, V. M., Rivera, M. E., Mehta, R. A., Vrtiska, T. J., & Rule, A. D. (2019). Predictors of Symptomatic Kidney Stone Recurrence After the First and Subsequent Episodes. Mayo Clin Proc, 94(2), 202-210. https://doi.org/10.1016/j.mayocp.2018.09.016

Published

2024-07-03

How to Cite

Onyango, V. C., Makanga, W. O., Kariuki, A. J., Kioko, B. M., Dido, M. D., Kamau, T. M., & Fryda, W. C. (2024). Recurrent Symptomatic Renal Stones Managed by Repeat Open Nephrolithotomy in a Rural Kenyan Hospital. American Journal of Medical Science and Innovation, 3(2), 18–22. https://doi.org/10.54536/ajmsi.v3i2.2896